ABSTRACT Substantial evidence supports the hypothesis that prions are misfolded, infectious, insoluble, and protease-resistant proteins (PrPRES) devoid of instructional nucleic acid that cause transmissible spongiform encephalopathies (TSEs).Protein misfolding cyclic amplification (PMCA) has provided additional evidence that PrPRes acts as a templa
Immunotherapy has revolutionized the treatment of cancer.Nevertheless, the majority of patients do not respond to therapy, meaning a deeper understanding of tumor immune evasion strategies is required to boost treatment efficacy.The vast majority of immunotherapy studies have focused on how treatment reinvigorates exhausted CD8+ T cells within the
Salpingo-enteric Tetherball fistula is a rare condition that can cause infertility.It occurs when there is an abnormal connection between the fallopian tube and the intestine.Accurate diagnosis can be made using hysterosalpingography.The case of a 40-year-old asymptomatic woman diagnosed with primary infertility and scheduled for a hysterosalpingog
Expression and transport activity of Sodium-dependent Vitamin C Transporter 2 (SVCT2) was shown in various tissues and organs.Vitamin C was shown to be cerebroprotective in several animal Pet Bowl models of stroke.Data on expression, localization and transport activity of SVCT2 after cerebral ischemia, however, has been scarce so far.Thus, we studi